Mike is a 46-year-old who presents with a complaint of “heartburn” for 3 months. He describes the pain as burning, located in the epigastric area.

Mike is a 46-year-old who presents with a complaint of “heartburn” for 3 months. He describes the pain as burning located in the epigastric area.

The pain improves after he takes an antacid or drinks milk. He has been taking either over-the-counter (OTC) famotidine or ranitidine off and on for the past 2 months, and he still has recurring epigastric pain.

He has lost 6 pounds since his last visit.

Assessment

His examination is unremarkable.

His blood pressure (BP) is 118/72 mm Hg. Laboratory values are: normal complete blood count (CBC) and a positive serum Helicobacter pylori test.

What would be the initial management plan for a patient with peptic ulcer disease caused by H. pylori?

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